Lumbar Interbody Fusion using Low-dose of Recombinant Human Bone Morphogenetic Protein-2 (rh-BMP2); Minimum 1-year Follow-up Results at A Single Institute

نویسندگان

چکیده

Journal of Minimally Invasive Spine Surgery & Technique (JMISST) is the official journal Korean Society (KOMISS) for publication research results about minimally invasive spinal surgery (MISS), including studies in endoscopic surgery, procedure degenerative spine disease, pain intervention, and fusion or trauma, neuroscience, neurology, molecular biology biomechanics etc. Articles with helpful information MISS such as reports rare cases technical review special devices equipment are also available

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Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein-2.

OBJECT Recombinant human bone morphogenetic protein-2 (rhBMP-2) is being increasingly used for spinal fusion. There are few data regarding its clinical safety, effectiveness, and clinical outcome when applied on an absorbable collagen sponge (ACS) in conjunction with allograft for transforaminal lumbar interbody fusion (TLIF). METHODS Seventy-four consecutive patients undergoing TLIF for dege...

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Allogeneic morphogenetic protein vs. recombinant human bone morphogenetic protein-2 in lumbar interbody fusion procedures: a radiographic and economic analysis

BACKGROUND Since the introduction of rhBMP-2 (Infuse) in 2002, surgeons have had an alternative substitute to autograft and its related donor site morbidity. Recently, the prevalence of reported adverse events and complications related to the use of rhBMP-2 has raised many ethical and legal concerns for surgeons. Additionally, the cost and decreasing reimbursement landscape of rhBMP-2 use have ...

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The effect of recombinant human bone morphogenetic protein-2 in single-level posterior lumbar interbody arthrodesis.

BACKGROUND In this prospective, randomized controlled trial, our objective was to assess both the clinical and radiographic effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in patients treated with an instrumented single-level posterior lumbar interbody arthrodesis with polyetheretherketone cages. METHODS Forty patients were randomized with a 1:1 ratio. Two patients who had ...

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Complications of Anterior Cervical Fusion using a Low-dose Recombinant Human Bone Morphogenetic Protein-2

OBJECTIVE There are several reports, which documented a high incidence of complications following the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in anterior cervical fusions (ACFs). The objective of this study is to share our experience with low-dose rhBMP-2 in anterior cervical spine. METHODS We performed a retrospective analysis of 197 patients who underwent anterior ce...

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Significance of early CT evaluation after lumbar interbody fusions using recombinant human bone morphogenetic protein-2.

Fusions Using Recombinant Human Bone Morphogenetic Protein-2 Williams et al proposed a radiographic protocol consisting of CT scans obtained at 3, 6, and 12 months, with an additional scanning at 24 months if a solid fusion was not seen earlier in evaluating lumbar interbody fusions (LIF) (with special emphasis on using the recombinant human bone morphogenetic protein-2 [rhBMP-2] as a bone graf...

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ژورنال

عنوان ژورنال: Journal of minimally invasive spine surgery and technique (Online)

سال: 2021

ISSN: ['2508-2043']

DOI: https://doi.org/10.21182/jmisst.2021.00094